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Cortisol, A.M.
Test Code4212
CPT Codes
82533
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Collect specimen between 7-9 a.m. Indicate the collection time on the specimen container and test requisition.
Collect 1 mL serum from a red-top (no gel) tube or serum separator tube; place in sterile plastic screw-capped vial(s).
Note: Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay
Collect 1 mL serum from a red-top (no gel) tube or serum separator tube; place in sterile plastic screw-capped vial(s).
Note: Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Reference Range
0-3 Days (infants) | |
Premature (31-35 Weeks) | ≤15.0 mcg/dL |
Term | ≤14.0 mcg/dL |
4 Days-1 Month | Not established |
2-11 Months 8 a.m. (7-9 a.m.) specimen | 3.0-23.0 mcg/dL |
1-17 Years 8 a.m. (7-9 a.m.) specimen | 3.0-25.0 mcg/dL |
>17 Years 8 a.m. (7-9 a.m.) specimen | 4.0-22.0 mcg/dL |
Clinical Significance
Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency).