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Gentamicin, Trough
Test Code8575
CPT Codes
80170
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect as a trough just prior to next dose.
Minimum Volume
0.2 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, or sodium heparin (green-top) tube, or lithium heparin (green-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: Unacceptable
Refrigerated: 7 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Reference Range
1.0-2.0 mg/L
Clinical Significance
Gentamicin is an aminoglycoside antibiotic used in the treatment of gram-positive and gram-negative bacterial infections, especially Pseudomonas, Proteus, Klebsiella and Staphylococcus. Gentamicin is potentially nephrotoxic and ototoxic. Serial monitoring of peak and trough serum levels may provide the clinician with information to maintain safe and therapeutic levels.