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Sickle Cell Screen
Test Code825
CPT Codes
85660
Preferred Specimen
4 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Instructions
Maintain specimen at room temperature. Do not centrifuge.
Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin F. In these cases it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered.
Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin F. In these cases it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: Unacceptable
Refrigerated: 14 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Clotted
Methodology
Solubility
Setup Schedule
Set up: Sun, Tues-Sat; Report available: Same day
Reference Range
Negative
Clinical Significance
This is a screening test to determine the presence of sickling hemoglobins. (e.g. hemoglobin-s, hemoglobin c-Harlem). It is important to detect Hb-S in order to determine which individuals are at risk of crisis when exposed to prolonged anoxia such as may occur during surgery, athletic programs or high altitude conditions.
