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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Doxycycline
Test Code94093
CPT Codes
80299<br><strong>This test is not available for New York patient testing</strong>
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Instructions
Specimens collected just before or within 15 minutes of the next antibiotic dose represent the trough level.
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST) • Other body fluids
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Wed, Sat; Report available: 1-5 days
Reference Range
Therapeutic range | 1-10 mcg/mL |
Clinical Significance
The concentration of antimicrobial agents in body fluids, most notably serum or plasma, are used to regulate therapy to ensure effective dosing (especially with oral agents where GI absorption is in question), to monitor accumulation to help minimize toxicity, and to help evaluate the pharmacokinetics of new agents. Both peak and trough levels obtained immediately after dosing or immediately prior to new dosing, respectively, may be monitored.