Beta Melanocyte Sitmulating Hormone

Test Code

91902

CPT Codes
83520<br /> This test is not available for New York patient testing.

Preferred Specimen

3 mL plasma collected in an EDTA (lavender-top) tube

Patient Preparation
Fasting specimen is preferred. Patient should be free from any medication for 2 days (48 hours).

Minimum Volume

1 mL

Transport Temperature

Frozen

Specimen Stability

Room temperature: Not stable
Refrigerated: 6 hours
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Received refrigerated

Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Pan Laboratories. This assay has been validated pursuant to the CLIA regulations. It has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule

Set up: Thurs a.m.; Report available: 3-8 days

Reference Range

0-150.0 pg/mL

Clinical Significance

Beta Melanocyte Stimulating Hormone is a 22 amino acid peptide produced from the prohormone, Proopiomelanocorticotropin. One of the fragments of Proopiomelanocorticotropin is b-Lipotropin which is further fragmented to form gamma Lipotropin and beta Endorphin. The gamma Lipotropin is then cleaved to form beta MSH. The major biological property of beta MSH is hyperpigmentation. Beta MSH is the major melanocortin in humans. Beta-Melanocyte Stimulating hormone has been found in high levels in patients with Cushings disease, ectopic ACTH producing tumors and also in some non-endocrine tumors.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.