|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Aldosterone, Adrenal Vein
Test Code95084
CPT Codes
82088
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.25 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top), EDTA (royal blue-top), sodium heparin (green-top), or lithium heparin (green-top) tube
Instructions
Draw blood in a red-top tube (no gel). Separate serum after clotting. Ship serum frozen. Do not submit glass tubes.
Draw "upright" samples at least 1/2 hour after patient sits up.
Draw "upright" samples at least 1/2 hour after patient sits up.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST) • Moderate to gross hemolysis
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 3-5 days
Reference Range
Reference ranges for the individual adrenal veins have not been established. Since results obtained on samples taken from various anatomical sites are variable, the following reference ranges apply only to measurements performed only on peripheral blood samples.
**Pediatric data from J Clin Endocrinol Metab. 1992;75:1491 and J CLin Endocrinol Metab. 1989; 69;1133-1136.
| Adult | |
| Upright 8:00-10:00 am | ≤28 ng/dL |
| Upright 4:00-6:00 pm | ≤21 ng/dL |
| Supine 8:00-10:00 am | 3-16 ng/dL |
| Pediatric | |
| 1-12 months** | 2-70 ng/dL |
| 1-4 years** | 2-37 ng/dL |
| 5-9 years | ≤9 ng/dL |
| 10-13 years | ≤21 ng/dL |
| 14-17 years | ≤35 ng/dL |
| Infants | |
| Premature (31-35 weeks)** | ≤144 ng/dL |
| Term** | ≤217 ng/dL |
| Tanner Stages** | |
| II-III Males | 1-13 ng/dL |
| II-III Females | 2-20 ng/dL |
| IV-V Males | 3-14 ng/dL |
| IV-V Females | 4-32 ng/dL |
**Pediatric data from J Clin Endocrinol Metab. 1992;75:1491 and J CLin Endocrinol Metab. 1989; 69;1133-1136.
Clinical Significance
Approximately 1-2% of individuals with primary hypertension have primary hyperaldosteronism characterized by hypokalemia (low potassium) and low direct renin. Because serum aldosterone concentrations vary due to dietary sodium intake and body positions, some physicians prefer measurement of 24-hour urine concentrations for aldosterone.
