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Homovanillic Acid (HVA), Random, Urine
Test Code19133
CPT Codes
83150<br><strong>Limited access code</strong>
Preferred Specimen
5 mL urine collected in a urine collection container
Patient Preparation
Administration of L-dopa may falsely increase homovanillic acid results. For 24 hours prior to specimen collection, the patient should not take L-dopa.
Minimum Volume
3 mL
Instructions
1. Collect a random urine specimen.
2. Adjust the urine pH to a level between 1 and 5 by adding 50% acetic acid or hydrochloric acid dropwise and checking the pH.
Note:
1. Patient's age is required.
2. All patients receiving L-dopa should be identified to the laboratory when this test is ordered.
3. Bactrim may interfere with detection of the analyte.
All patients taking Bactrim should be identified to the laboratory when this test is ordered.
2. Adjust the urine pH to a level between 1 and 5 by adding 50% acetic acid or hydrochloric acid dropwise and checking the pH.
Note:
1. Patient's age is required.
2. All patients receiving L-dopa should be identified to the laboratory when this test is ordered.
3. Bactrim may interfere with detection of the analyte.
All patients taking Bactrim should be identified to the laboratory when this test is ordered.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 28 days
Frozen: 180 days
Refrigerated: 28 days
Frozen: 180 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
Setup Schedule
Set up: Mon-Fri; Report available: 3-5 days
Reference Range
See Laboratory Report
Clinical Significance
Screening children for catecholamine-secreting tumors using a random urine collection when requesting homovanillic acid only.
Monitoring neuroblastoma treatment.
Screening patients with possible inborn errors of catecholamine metabolism.
Monitoring neuroblastoma treatment.
Screening patients with possible inborn errors of catecholamine metabolism.
