Cytomegalovirus (CMV) Quantitative PCR

Test Code

18587

CPT Codes
87497<br>Restricted Client Code

Preferred Specimen

2 mL bronchoalveolar lavage collected in a sterile screw-top tube

Minimum Volume

0.5 mL

Instructions

Collect in a sterile, screw-top tube. Can be shipped at ambient or frozen temperature Monday through Friday. Specimens shipped at ambient temperature must be received within 96 hours of collection.

Ship Monday through Friday. Friday shipments must be labeled for Saturday delivery. All specimens must be labeled with patient's name and collection date.

Transport Temperature

Frozen -70° C

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen -20° C: Unacceptable
Frozen -70° C: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Whole blood frozen • Grossly hemolyzed plasma/serum specimens • Specimens beyond their acceptable length of time from collection as listed in the specimen handling • Specimens received in trap containers • Specimen types other than those listed

Methodology
Polymerase Chain Reaction (PCR)

FDA Status
This test was developed and its performance characteristics determined by Eurofins Viracor. It has not been cleared or approved by the U.S. Food and Drug Administration. Results should be used in conjunction with clinical findings, and should not form the sole basis for a diagnosis or treatment decision.

Setup Schedule

Set up: Mon-Sat; Report available: 8-12 hours from receipt of specimen

Reference Range

Not Detected

Clinical Significance

Cytomegalovirus (CMV) is an important pathogen in the transplant setting causing pneumonitis, colitis, hepatitis, CNS disease, neutropenia, and disseminated disease. Prior to the availability of rapid and sensitive DNA PCR, CMV was a leading cause of morbidity and mortality in the transplant population. Quantitative CMV DNA PCR can be used for early detection of CMV reactivation, primary infections, and monitoring response to treatment.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.