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Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum
Test Code12870
CPT Codes
84182, 86255 (x26), 86341, 86596<br>Restricted Client Code
Preferred Specimen
4 mL serum
Patient Preparation
For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment.
Minimum Volume
3 mL
Instructions
Centrifuge and aliquot serum into a plastic vial.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 28 days
Refrigerated: 28 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia • Gross icterus
Methodology
Immunoblot • Indirect IFA by CBA (Cell binding Assay) • Interpretation • Radioimmunoassay • Western Blot
FDA Status
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
Setup Schedule
Set up: Mon-Sun (Reflex tests: Varies); Report available: 8-12 days
Reference Range
See Laboratory Report
Clinical Significance
Evaluating patients with suspected paraneoplastic or other autoimmune movement disorders including patients with ataxia, brainstem encephalitis, chorea, dyskinesias, myoclonus, and parkinsonism using serum specimens.

