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Barbiturates, Confirmation, Blood
Test Code408501
CPT Codes
82205
Includes
Amobarbital, Butabarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 1 year
Refrigerated: 14 days
Frozen: 1 year
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Reference Range
See Laboratory Report
Clinical Significance
Barbiturates are extensively used for hypnotics, sedatives, and anesthetics, and are readily absorbed from the stomach. Duration of action of Barbiturates in therapeutic doses varies from: 8-16 hours (long acting e.g., Phenobarbital); 4-8 hours (intermediate acting e.g., Amobarbital); 3-6 hours (short acting e.g., Pentobarbital). Barbiturates may enhance other CNS depressants, such as Ethanol, Morphine derivatives, tranquilizers, and Resperine.