Asparaginase Activity

Test Code

13975

CPT Codes
82657<br><strong>This test is not available for Rhode Island patient testing.</strong>

Preferred Specimen

1 mL serum or
1 mL plasma collected in an EDTA K2 (lavender-top) tube

Minimum Volume

0.3 mL

Other Acceptable Specimens

Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube

Instructions

Use standard collection procedures for serum and plasma

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 3 years

Methodology
Coupled Enzyme Kinetic Reaction

FDA Status
This test was developed and its performance characteristics determined by NEXT Bio Research Service, LLC. It has not been cleared or approved by the US Food and Drug Administration.

Setup Schedule

Set up: Mon-Fri; Report available: Same day

Reference Range

See Laboratory Report

Clinical Significance

The L-asparaginase assay is a laboratory developed test (LDT) to determine the enzyme activity of L-asparaginase in patients who have been treated with Oncaspar®, Asparlas®, Erwinaze®, or Rylaze®, all frontline chemotherapeutics for the treatment of acute lymphoblastic leukemia (ALL). Our assay has been validated under GLPs and CLIA requirements and is performed in our CLIA certified laboratory to monitor the asparaginase activity level during a patient's treatment.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.