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BRAF V600E Mutation, IHC without Interpretation
Test Code92295
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded block submitted in an IHC specimen transport kit
Minimum Volume
3 slides
Other Acceptable Specimens
5 unstained, positively (+) charged slides
Instructions
Do not reject
Transport Temperature
Room temperature
Specimen Stability
Paraffin block
Room temperature: 5 years
Refrigerated: 5 years
Frozen: Unacceptable
Slides
Room temperature: 45 days
Refrigerated: 45 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
No tumor in blocks or slides
Methodology
Immunohistochemistry
Setup Schedule
Set up: Daily; Report available: 1-2 days
Reference Range
See Laboratory Report
Clinical Significance
This mutated protein is expressed in a variety of tumors, including most commonly in melanoma, papillary thyroid carcinoma, colorectal carcinoma, ovarian serous carcinoma and hairy cell leukemia.