BRAF V600E Mutation, IHC without Interpretation

Test Code
92295


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded block submitted in an IHC specimen transport kit


Minimum Volume
3 slides


Other Acceptable Specimens
5 unstained, positively (+) charged slides


Instructions
Do not reject


Transport Temperature
Room temperature


Specimen Stability

Paraffin block
Room temperature: 5 years
Refrigerated: 5 years
Frozen: Unacceptable

Slides
Room temperature: 45 days
Refrigerated: 45 days
Frozen: Unacceptable



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
No tumor in blocks or slides


Methodology
Immunohistochemistry

Setup Schedule
Set up: Daily; Report available: 1-2 days


Reference Range
See Laboratory Report


Clinical Significance
This mutated protein is expressed in a variety of tumors, including most commonly in melanoma, papillary thyroid carcinoma, colorectal carcinoma, ovarian serous carcinoma and hairy cell leukemia.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.