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BAP1, IHC with Interpretation
Test Code39872
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded block submitted in an IHC specimen transport kit
Minimum Volume
3 slides
Other Acceptable Specimens
5 unstained, positively (+) charged slides
Instructions
Please include surgical pathology report. Do not reject.
Transport Temperature
Room temperature
Specimen Stability
Paraffin block
Room temperature: 5 years
Refrigerated: 5 years
Frozen: Unacceptable
Slides
Room temperature: 45 days
Refrigerated: 45 days
Frozen: Unacceptable
Room temperature: 5 years
Refrigerated: 5 years
Frozen: Unacceptable
Slides
Room temperature: 45 days
Refrigerated: 45 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
No tumor in blocks or slides
Methodology
Immunohistochemistry
Setup Schedule
Set up: Daily; Report available: 2-4 days
Reference Range
See Laboratory Report
Clinical Significance
Loss of BAP1 expression can be useful in distinguishing benign from malignant mesothelial proliferations, and in identifying atypical Spitz tumor and uveal melanoma.
