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Thyroid Stimulating Hormone
MessagePerformed in Chemistry
Test Code
TSH
Alias/See Also
TSH, High Sensitivity
CPT Codes
83519
Preferred Specimen
Green Top LiHep, Plasma
WyMCC and BLMC - SST
WyMCC and BLMC - SST
Other Acceptable Specimens
Lavender Top EDTA, Gold/SST or Red Top
Specimen Stability
Refrigerated 7 days
Frozen 1 month
Frozen 1 month
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Report Available
Less than 4 hours
Reference Range
Age | Male/Female |
0-4 days | 3.20-35.00 |
4 days-1 month | 1.70-9.10 |
1 month-1 yr | 0.80-8.20 |
1-6 yrs | 0.60-7.40 |
6-11 yrs | 0.50-5.40 |
11-20 yrs | 0.30-4.00 |
20-150 yrs | 0.45-4.50 |
Clinical Significance
TSH secretion by the anterior pituitary is controlled by thyrotropin releasing hormone, a tripeptide produced by the
hypothalamus. TSH stimulates the production of thyroxine (T4) and triiodothyronine (T3) by the thyroid gland. The
circulating free fractions of T4 and T3 in turn regulate the secretion of TSH by a negative feedback mechanism at the
pituitary and possibly the hypothalamus. The diagnosis of overt hypothyroidism by the finding of a low total T4 or free T4
concentration is readily confirmed by a raised TSH concentration.
Measurement of low or undetectable TSH concentrations may assist the diagnosis of hyperthyroidism, where
concentrations of T4 and T3 are elevated and TSH secretion is suppressed.
hypothalamus. TSH stimulates the production of thyroxine (T4) and triiodothyronine (T3) by the thyroid gland. The
circulating free fractions of T4 and T3 in turn regulate the secretion of TSH by a negative feedback mechanism at the
pituitary and possibly the hypothalamus. The diagnosis of overt hypothyroidism by the finding of a low total T4 or free T4
concentration is readily confirmed by a raised TSH concentration.
Measurement of low or undetectable TSH concentrations may assist the diagnosis of hyperthyroidism, where
concentrations of T4 and T3 are elevated and TSH secretion is suppressed.
Performing Laboratory
On-site