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Lamotrigine
MessagePerformed at BUMCP
Test Code
LAMO
Alias/See Also
Lamictal
CPT Codes
80175
Preferred Specimen
6.0 mL Red Top only - serum
Minimum Volume
1.0 mL serum
3.0 mL whole blood
3.0 mL whole blood
Other Acceptable Specimens
Li or NA Heparin, EDTA - For consistency, should use the same tube type for each individual patient.
Instructions
Draw 1/2 to 1 hour before next dose at steady state.
Allow specimen to fully clot before centrifuging.
Allow specimen to fully clot before centrifuging.
Transport Temperature
Refrigerated
FDA Status
LDT
Report Available
Test availability and turn around time is 5 - 7 days.
Clinical Significance
Lamotrigine (LAMICTAL®, 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine) is an anti-convulsant
drug approved for use in the treatment of epilepsy and is often prescribed as monotherapy or as one
component of a multiple anti-epileptic drug therapy. Lamotrigine was approved by the United States
Food and Drug Administration (FDA) in late 1994 as an adjunctive therapy for partial seizures.
Lamotrigine has since gained indications as monotherapy for partial seizures and also as a treatment
for bipolar disorder. Lamotrigine has also accumulated a solid safety record in pregnancy, leading to
the common use of this AED in pregnant women with epilepsy.
drug approved for use in the treatment of epilepsy and is often prescribed as monotherapy or as one
component of a multiple anti-epileptic drug therapy. Lamotrigine was approved by the United States
Food and Drug Administration (FDA) in late 1994 as an adjunctive therapy for partial seizures.
Lamotrigine has since gained indications as monotherapy for partial seizures and also as a treatment
for bipolar disorder. Lamotrigine has also accumulated a solid safety record in pregnancy, leading to
the common use of this AED in pregnant women with epilepsy.
