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Dilantin Level, Free
MessagePerformed at BUMCP and BUMCT
Test Code
PTNFREE
Alias/See Also
Dilantin
Preferred Specimen
Draw 2.1 - 6.0ml Green top Li - plasma
Separate and aliquot plasma - send Plasma to BUMCP
Note: Do not send in mother tube (cannot sit on gel)
Separate and aliquot plasma - send Plasma to BUMCP
Note: Do not send in mother tube (cannot sit on gel)
Instructions
Samples must be centrifuged within an hour of collection and removed from gel and cells within 4 hours of collection.
Transport Temperature
Refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens recieved in mother tube will be rejected, must be plasma aliquot
Setup Schedule
Daily.
If sending to BUMCP, turnaround time may be greater than 4 hours.
If sending to BUMCP, turnaround time may be greater than 4 hours.
Clinical Significance
Phenytoin (diphenylhydantoin) has been used extensively for seizure control in patients having both grand mal epilepsy (major
motor), cortical focal seizures, and temporal lobe epilepsy. Serum level monitoring of the drug is essential in order to achieve
maximal seizure control while maintaining minimal blood levels. Because of individual variation in absorption and metabolism,
optimum levels may vary.
motor), cortical focal seizures, and temporal lobe epilepsy. Serum level monitoring of the drug is essential in order to achieve
maximal seizure control while maintaining minimal blood levels. Because of individual variation in absorption and metabolism,
optimum levels may vary.
