Alpha-2-Macroglobulin

Test Code

A2M

Quest Code

228

CPT Codes
83883

Preferred Specimen

1 mL fasting serum

Patient Preparation
Overnight fasting is preferred.

Minimum Volume

0.5 mL

Instructions

Avoid hemolysis

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature

Methodology
Fixed Rate Time Nephelometry

Setup Schedule

Tuesday-Saturday Morning
Report available: 2 Days

Reference Range

106-279 mg/dL

Clinical Significance

Alpha-2-Macroglobulin is produced in the liver. Increased concentrations are associated with patients with some chronic liver diseases, nephrotic syndrome, and diabetes. Decreased concentrations are associated with patients with pancreatitis, rheumatoid arthritis, and multiple myeloma.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.