Fungitell (1-3) B-D-Glucan Assay

Test Code

Quest Code

CPT Codes

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Draw blood in plain red-top tube or serum separator tube, spin down, then aliquot off into a cryogenic vial (DNAse, RNAse, pyrogen-free). Glucan free tubes are acceptable.

Transport Container
Cryogenic vial (DNAse, RNAse, pyrogen-free)

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Icteric • Turbid serum • Specimens other than serum • Glass tubes

Protease Zymogen-based Colorimetric

Setup Schedule
Set up: Daily; Report available: 1-2 days

Reference Range
<60 pg/mL

Clinical Significance
Invasive Fungal Infections (IFI) are increasing, especially among immunocompromised patients. Most pathogenic fungi have (1-3)-beta-D-glucan in their cell walls and minute quantities are sloughed into the bloodstream and appear in the serum in cases of IFI. Monitoring serum (1-3)-beta-D-glucan for evidence of elevated and rising levels provides a convenient surrogate marker for IFI.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.