Anti-Thyroglobulin Antibody (TgAb)

Test Code

THYAB-USC

Alias/See Also

THYABUSC

CPT Codes
86800

Preferred Specimen

Large Red Top; Serum

Minimum Volume

0.5 mL Refrigerated serum

Transport Container

Aliquot tube; 1ml serum

Transport Temperature

Refrigerated

Specimen Stability

Stored at 2 - 8°C until used; Stable if frozen at - 20°C

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Whole blood/Plasma; Slightly and moderately lipemic, hemolyzed or icteric samples are acceptable. Samples that are grossly lipemic, icteric or hemolyzed are not acceptable.

Methodology

Radioimmunoassay

Setup Schedule

Monday - Friday

Report Available

Next Working Day

Reference Range

<0.4 U/mL

Clinical Significance

This highly sensitive, direct radioimmunoassay system is based on the use of a highly purified, stable preparation of 125I labeled Thyroglobulin. The assay is standardized against the MRC Thyroglobulin Auto-antibody First International Reference Preparation (Coded 65/93). Measurement of thyroglobulin auto-antibodies can be of considerable value in the diagnosis of thyroid diseases,
such as autoimmune thyroiditis, Graves' disease, endemic goiter and subacute thyroiditis. These measurements when used as part of a thyroid autoimmune diagnostic profile, which would include Anti Thyroid Peroxidase Antibody and Thyrotropin Receptor antibody, can be very useful in the differential diagnosis and management of thyroid disease. TgAb is always to be run in conjunction with Thyroglobulin (Tg) sera in order to conform to NACB guidelines (Thyroid 13:1, 2003).

Performing Laboratory
University of Southern California

Additional Information
Test Info

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.