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Drug Screen Panel 5, Meconium
Test CodeMECDRG
Quest Code
45489
CPT Codes
80307
Includes
Amphetamines, Cocaine Metabolite, Marijuana, Opiates, PCP (Phencyclidine)
Preferred Specimen
5 grams meconium submitted in a sterile leak-proof feces container
Minimum Volume
1 g
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
Immunoassay with Chromatography/Mass Spectrometry
FDA Status
Confirmation: This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Fri; Report available: 2 days
Reference Range
See Laboratory Report
Clinical Significance
Meconium contains the amniotic fluid swallowed by the fetus in the last half of pregnancy and is released as the first stools after birth. Meconium is easier to collect than neonatal urine and provides a much longer window of exposure of up to 20 weeks. Meconium is an effective biological marker of in utero drug exposure, and can provide insights leading to improved neonatal outcomes, as well as provide evidence to ensure appropriate rehabilitation of mothers suffering from addiction. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive mass spectroscopy (MS) methodology. Test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the amount of drug that the neonate was exposed.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153