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Vitamin B1 (Thiamine) Whole Blood
MessageProtect from light. Freeze entire lavender tube.
Do not aliquot.
**CANNOT BE PERFORMED AS AN ADD-ON TEST**
Do not aliquot.
**CANNOT BE PERFORMED AS AN ADD-ON TEST**
Test Code
VB1WB
Quest Code
5042
Alias/See Also
VB1RBC
CPT Codes
84425
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube, protected from light
Patient Preparation
Overnight fasting is required
Minimum Volume
1 mL
Instructions
wrap tube in aluminum foil to protect from light. Freeze immediately.
Transport Container
see above - wrap tube in aluminum foil to protect from light.
Quest preferred "Amber transport tube" (not required)
Quest preferred "Amber transport tube" (not required)
Transport Temperature
Frozen
Specimen Stability
Room temperature: 8 hours
Refrigerated: 5 days
Frozen: 35 days
Refrigerated: 5 days
Frozen: 35 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature and not protected from light • Received refrigerated and not protected from light
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 2-3 days
Reference Range
78-185 nmol/L
Clinical Significance
Vitamin B1 is required for branched-chain amino acid and carbohydrate metabolism. Vitamin B1 deficiency is most often due to alcoholism or chronic illness. In the early stage, patients with vitamin B1 deficiency exhibit anorexia, irritability, apathy, and generalized weakness. Prolonged deficiency causes beriberi.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
