| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Sex Hormone Binding Globulin
Test CodeSHBG
Quest Code
30740
CPT Codes
84270
Preferred Specimen
0.7 mL serum
Minimum Volume
0.5 mL
Instructions
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Plasma
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Daily; Report available: 1-2 days
Reference Range
| <3 Years | Not established | |||
| Male (nmol/L) | Female (nmol/L) | |||
| 3-9 Years | 32-158 | 32-158 | ||
| 10-13 Years | 20-166 | 24-120 | ||
| 14-17 Years | 20-87 | 12-150 | ||
| 18-55 Years | 10-50 | 17-124 | ||
| >55 Years | 22-77 | 14-73 | ||
Clinical Significance
Testosterone, dihydrotestosterone and estrogens circulate in serum bound to Sex Hormone Binding Globulin (SHBG). SHBG concentrations are increased in pregnancy, hyperthyroidism, cirrhosis, oral estrogen administration and by certain drugs. Concentrations are decreased by testosterone, hypothyroidism, Cushings syndrome, acromegaly and obesity.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
