A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
JC Polyoma Virus DNA, Qual. PCR
Test CodeJCPCR
Quest Code
17220
CPT Codes
87798
Preferred Specimen
0.7 mL plasma collected in an EDTA (lavender-top) tube, or EDTA PPT (white-top) tube
Minimum Volume
0.3 mL plasma • 0.3 mL serum
Other Acceptable Specimens
Plasma collected in: ACD solution A (yellow-top) tube • 0.7 mL Serum
Transport Temperature
Frozen
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 1 day
Reference Range
Not detected
Clinical Significance
JC polyoma virus is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC polyoma virus DNA in CSF, urine or plasma. Detection of virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JVC can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153