Fluoxetine (Prozac)

Test Code

FLUOX

Quest Code

8389

CPT Codes
80299

Includes

Norfluoxetine, Fluoxetine and Total

Preferred Specimen

1 mL serum

Patient Preparation
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube • Serum collected in a no additive (royal blue-top) tube

Instructions

Do not use gel barrier/serum separator tubes.

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 5 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Gel barrier/Serum Separator Tube (SST^®)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues, Sat a.m.; Report available: 3-6 days

Reference Range

Total

300-1150 mcg/L

Clinical Significance

Fluoxetine is an antidepressant drug that is also used in the treatment of bulimia nervosa and obsessive-compulsive disorder. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.

Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.