Clonazepam (Klonopin)

Test Code

CLON

Quest Code

340

CPT Codes
80299

Preferred Specimen

2 mL serum collected in a red-top tube (no gel)

Patient Preparation
Collect at trough concentration, immediately before the administration of the next dose

Minimum Volume

1 mL

Other Acceptable Specimens

Serum collected in a no additive (royal blue-top) tube • Plasma collected in an: EDTA (lavender-top), or (royal blue-top), or sodium heparin or lithium (green-top) tube

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gel barrier/Serum separator tube (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues, Thurs, Sat; Report available: 2-4 days

Reference Range

30-60 mcg/L

Clinical Significance

Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.