Ceruloplasmin

Test Code

CER

Quest Code

326

CPT Codes
82390

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 14 days
Frozen: 90 days

Methodology
Immunoturbidimetric Assay

Setup Schedule

Set up: Mon-Sat p.m.; Report available: Next day

Limitations

Since ceruloplasmin is an acute phase reactant, caution is necessary when inflammation or infection are present.

Reference Range

Age	Male (mg/dL)	Female (mg/dL)
0-30 Days	8-25	3-28
31 Days-11 Months	15-48	15-43
1-3 Years	25-56	29-54
4-6 Years	29-56	26-54
7-9 Years	25-52	23-48
10-12 Years	21-51	21-48
13-15 Years	20-50	21-46
16-18 Years	20-45	22-50
>18 Years	18-36	18-53

Clinical Significance

Decreased levels of ceruloplasmin are found in Wilson's Disease, fulminant liver failure, intestinal malabsorption, renal failure resulting in proteinuria, chronic active hepatitis and malnutrition. Elevated levels are found in primary biliary cirrhosis, pregnancy (first trimester), oral contraceptive use and in acute inflammatory conditions since ceruloplasmin is an acute phase reactant.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.