| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Beta-2 Transferrin
Test CodeB2T
Quest Code
10640
CPT Codes
86335
Preferred Specimen
0.5 mL body fluid collected in a sterile, plastic, leak-proof transport tube
Minimum Volume
0.2 mL
Other Acceptable Specimens
See Collection Instructions
Instructions
• Indicate specimen source
• If direct collection is not feasible, specimen may be collected using plain cotton swab and submitted in a sterile, plastic leak-proof transport tube.
• If submitting syringe, remove needle and cap the syringe to avoid specimen leakage.
• Do not collect specimen with a culture swab.
• Do not add any liquid to the swab.
Additional Information
•Specimens contaminated with salivary fluid degrade the beta-2 transferrin. These specimens should be frozen immediately following collection and should be kept frozen until testing is performed.
• Specimens collected with additives yield uninterpretable results and will be rejected.
• If direct collection is not feasible, specimen may be collected using plain cotton swab and submitted in a sterile, plastic leak-proof transport tube.
• If submitting syringe, remove needle and cap the syringe to avoid specimen leakage.
• Do not collect specimen with a culture swab.
• Do not add any liquid to the swab.
Additional Information
•Specimens contaminated with salivary fluid degrade the beta-2 transferrin. These specimens should be frozen immediately following collection and should be kept frozen until testing is performed.
• Specimens collected with additives yield uninterpretable results and will be rejected.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 15 days
Refrigerated: 30 days
Frozen: 60 days
Refrigerated: 30 days
Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens collected with additives
Methodology
Electrophoresis • Immunofixation
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 1-2 days
Reference Range
Not detected
Clinical Significance
Presence of Beta-2 Transferrin (B2T) in nose and ear secretions is indicative of cerebrospinal fluid (CSF) leakage. B2T is used as a marker of CSF leakage for the diagnosis of rhinorrhea or otorrhea as a result of head trauma, tumor, congenital malformation, surgery etc. Prompt diagnosis and localization helps localization and life-threatening CNS infections.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
