Immunoglobulins (IgG, IgA, IgM)

Test Code
IGGAM


Quest Code
7083


CPT Codes
82784 (x3)

Includes
IgA, IgG, IgM


Preferred Specimen
2 mL serum


Minimum Volume
0.5 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 90 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Immunoturbidimetric

Setup Schedule
Set up: Daily; Report available: 1 day


Reference Range
IgA, Serum
Cord Blood 1-3 mg/dL
1-28 days 2-40 mg/dL
1-3 months 3-40 mg/dL
4-6 months 7-47 mg/dL
7-11 months 12-53 mg/dL
1 year 20-73 mg/dL
2 years 20-99 mg/dL
3-5 years 22-140 mg/dL
6-8 years 31-180 mg/dL
9-11 years 33-200 mg/dL
12-16 years 36-220 mg/dL
17-60 years 47-310 mg/dL
≥61 years 70-320 mg/dL

IgG, Serum
Cord Blood 600-1600 mg/dL
1-28 days 250-600 mg/dL
1-3 months 200-600 mg/dL
4-6 months 160-590 mg/dL
7-11 months 160-800 mg/dL
1 year 280-1040 mg/dL
2 years 330-1120 mg/dL
3-5 years 390-1360 mg/dL
6-8 years 440-1470 mg/dL
9-11 years 480-1530 mg/dL
12-16 years 500-1590 mg/dL
17-60 years 600-1640 mg/dL
≥61 years 600-1540 mg/dL

IgM, Serum
Cord Blood 6-25 mg/dL
1-28 days 10-50 mg/dL
1-3 months 10-72 mg/dL
4-6 months 12-86 mg/dL
7-11 months 13-120 mg/dL
1 year 23-130 mg/dL
2 years 25-135 mg/dL
3-5 years 26-150 mg/dL
6-8 years 25-150 mg/dL
9-11 years 40-160 mg/dL
12-16 years 41-170 mg/dL
≥17 years 50-300 mg/dL


Clinical Significance
Elevations of IgG, A and/or M are seen in generalized hypergammaglobulinemia, chronic inflammatory conditions and in lymphoproliferative diseases such as multiple myeloma, lymphoma and leukemias. Decreased levels are found in immunodeficiency states, generalized hypogammaglobulinemia and in unrecognized pediatric patients.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.