Histamine, Plasma

Test Code

HISPL

Quest Code

36586

CPT Codes
83088

Preferred Specimen

1 mL plasma collected in an EDTA tube (lavender-top)

Patient Preparation
Avoid taking allergy causing drugs, antihistamines, oral corticosteroids and substances which block H2 receptors 24 hours prior to collection.

Minimum Volume

0.5 mL

Instructions

Centrifuge immediately and freeze in plastic screw-cap vial.

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lipemia • Received room temperature • Received refrigerated

Methodology
Enzyme Immunoassay (EIA)

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

Set up: Tues, Fri; Report available: 2-6 days

Reference Range

≤1.8 ng/mL

Clinical Significance

Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.