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Thyroxine Binding Globulin (TBG)
Test CodeTBG
Alias/See Also
Thyroxine Binding Globulin Quest Code 4352
CPT Codes
84442
Preferred Specimen
1 mL serum collected in a serum separator tube (SST)
Minimum Volume
0.5 mL
Other Acceptable Specimens
1 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Chemiluminescence
Setup Schedule
Daily evenings
Report Available
Same day
Clinical Significance
The measurement of TBG can be used to establish the presence of TBG deficiency or excess suggested by abnormal Total serum T 4 and T 3 concentrations in the presence of normal free levels of these hormones. Definitive documentation of a TBG derangement may avoid unnecessary diagnostic procedures and therapy in individuals with harmless congenital TBG anomalies, and in their relatives. Performing Laboratory Quest Diagnostics Nichols Institute Chantilly, VA
