S. pneumoniae IgG (14 Serotypes)

Test Code

SPNEUG7

Alias/See Also

Streptococcus pneumoniae IgG Ab (14 Serotypes) Strep pneumoniae IgG Antibody Pneumococcal Antibody, 14 Serotypes Quest Code 19564

CPT Codes
86317 (x14)

Includes

Serotypes 1, 3, 4, 5, 8, 9 (9N), 12 (12F), 14, 19 (19F), 23 (23F), 26 (6B), 51 (7F), 56 (18C), 68 (9V)

Preferred Specimen

0.5 mL serum collected in a serum separator tube (SST)

Minimum Volume

0.25 mL

Other Acceptable Specimens

0.5 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 90 days

Methodology
Multi-Analyte Immunodetection (MAID)

Setup Schedule

Monday-Saturday a.m.

Report Available

2-4 days

Clinical Significance

The MAID procedure measures IgG antibodies recognizing 14 type-specific pneumococcal polysaccharide antigens included in the polyvalent vaccine (1, 3, 4, 5, 8, 9, 12, 14, 19, 23, 26, 51, 56, and 68). A 2- to 4-fold increase in type-specific antibodies measured 4-6 weeks after vaccination is expected in immunocompetent adults. The number of serotypes for which a 2- to 4-fold increase is observed varies greatly among individuals; a consensus panel has suggested that individuals older than 5 years should respond to at least approximately 70% of pneumococcal serotypes. Adults > 65 years old may exhibit a smaller (< 2-fold) increase in type-specific antibody levels.

Performing Laboratory
Focus Diagnostics, Inc.
San Juan Capistrano, CA

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.