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Fibrinogen
MessageTest performed at York Hospital Laboratory.
Test Code
FIB
CPT Codes
85384
Preferred Specimen
Whole blood collected in a 3.2% sodium citrate (light blue-top) tube NOTE: This tube can also be used for in-house D-Dimer, PT, and/or PTT testing.
Other Acceptable Specimens
0.5 mL platelet-poor plasma collected in a 3.2% sodium citrate (blue-top) tube, transferred to a plastic screw-cap vial
Instructions
Draw blood into light blue-top tube, filling tube to mark indicated on the tube. Do not overfill.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 8 hours
Refrigerated: Not recommended
Frozen (plasma): 1 month
Frozen (whole blood): unacceptable
Refrigerated: Not recommended
Frozen (plasma): 1 month
Frozen (whole blood): unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimen
Refrigerated specimen
Refrigerated specimen
Methodology
Clotting Assay
Setup Schedule
Daily
Report Available
Next Day Available STAT 1 Hour
Reference Range
190-495 mg/dL Critical Values <100 mg/dL or >700 mg/dL
Clinical Significance
Elevated concentrations of fibrinogen in the plasma are to be expected in inflammatory processes, after major trauma surgery (acute-phase protein), in metastasizing tumors, and after serious operations. Diminished levels of fibrinogen can occur in consumption coagulopathies, (e.g., DIC or disseminated intravascular coagulation), primary hyperfibrinolysis, liver damage, and genetic deficiency (i.e., hypo- or dysfibrinogenemia).
