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Vancomycin (Trough)
MessageTest performed at York Hospital Laboratory.
Test Code
VANCT
CPT Codes
80202
Preferred Specimen
0.2 mL Serum
Instructions
Collect as a trough just before next dose.
Include time of last dose with specimen.
Protect specimen from prolonged exposure to light and direct sunlight.
Include time of last dose with specimen.
Protect specimen from prolonged exposure to light and direct sunlight.
Transport Container
Red-top tube (no gel)
Serum Separator Tube also acceptable
Serum Separator Tube also acceptable
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 2 hours
Refrigerated: 3 days
Frozen: 14 days
Refrigerated: 3 days
Frozen: 14 days
Methodology
Immunoassay
Setup Schedule
Daily
Report Available
Next Day
Available STAT 1 Hour
Available STAT 1 Hour
Reference Range
15.00-20.00 ug/mL
Detection Limit: 5.00 ug/mL
Critical Values
>20.00 ug/mL
Detection Limit: 5.00 ug/mL
Critical Values
>20.00 ug/mL
Clinical Significance
Vancomycin is used in the treatment of serious or severe infections caused by gram-positive organisms resistant to penicillins, cephalosporins, or other antimicrobial agents. The risk of ototoxicity and nephrotoxicity is increased in patients with impaired renal function, and in patients receiving concurrent aminoglycoside treatment. Serum vancomycin measurements are used in the diagnosis and treatment of vancomycin overdose and in monitoring levels of vancomycin to ensure appropriate therapy.