Creatinine Clearance, 24 Hr.Urine

Message

Test performed at York Hospital Laboratory.

Test Code

UCC24

CPT Codes
82570, 82575

Includes

Total Volume Creatinine, Serum Creatinine, Urine Creatinine Clearance Creatinine, 24-Hour Urine eGFR

Preferred Specimen

5 mL aliquot of a well mixed 24-hour urine, submitted in a plastic leakproof container and 0.2 mL serum collected in a serum separator tube (SST)

Other Acceptable Specimens

Alternatives to serum collected in serum separator tube (SST) 0.2 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial 0.2 mL plasma collected in a lithium heparin (green-top) gel separator tube

Instructions

Serum creatinine must be collected within 48 hours of the 24-hour urine.

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 3 days
Refrigerated: 5 days
Frozen: Indefinite

Methodology
Spectrophotometry

Setup Schedule

Daily

Report Available

Next Day

Reference Range

Creatinine Clearance Normal Ranges (mL/min)

Age	Male	Female
<30 Years	94 - 140	72 - 110
30-39 Years	59 - 137	71 - 121
40-49 Years	76 - 120	50 - 102
50-59 Years	67 - 109	50 - 102
60-69 Years	54 - 98	45 - 75
70-79 Years	49 - 79	37 - 61
80-89 Years	30 - 60	27 - 55
>89 Years	26 - 44	26 - 42

Clinical Significance

Daily creatinine production is fairly constant except when there is a massive injury to muscle. The kidneys excrete creatinine very efficiently and blood levels and daily urinary excretion of creatinine fluctuate very little in healthy normal people. Since blood and daily urine excretion of creatinine show minimal fluctuation, creatinine excretion is useful in determining whether 24-hour urine specimens for other analytes (e.g. protein) have been completely and accurately collected.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.