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Theophylline
MessageTest performed at York Hospital Laboratory.
Test Code
THEO
CPT Codes
80198
Preferred Specimen
0.2 mL serum collected in a serum separator tube (SST)
Other Acceptable Specimens
0.2 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial 0.2 mL plasma collected in a lithium heparin (green-top) gel separator tube
Instructions
Separate serum or plasma from the cells within 4 hours of collection.
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 2 months
Refrigerated: 7 days
Frozen: 2 months
Methodology
Spectrophotometry
Setup Schedule
Daily
Report Available
Next Day
Reference Range
10.0-20.0 mg/L Detection Limit: 1.0 mg/L Critical Values >20.0 mg/dL
Clinical Significance
Theophylline is a drug used in the treatment of asthma. Theophylline is an effective bronchodilator. Theophylline measurements are used to monitor patient compliance and therapy and to diagnose potential overdose. Toxic effects include nausea, vomiting, diarrhea, headache, tachycardia, arrhythmias, and convulsions.