PSA

Message

Test performed in York Hospital Laboratory.

Test Code

PSA

Alias/See Also

Prostate Specific Antigen

CPT Codes
84153

Preferred Specimen

0.2 mL serum collected in a serum separator tube (SST)

Other Acceptable Specimens

0.2 mL serum collected in a no additive (red-top) tube, transferred to a plastic aliquot tube 0.2 mL plasma collected in a lithium heparin (green-top) tube

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 4 hours
Refrigerated: 7 days
Frozen: 4 weeks

Methodology
Chemiluminescence

Setup Schedule

Daily

Report Available

Next Day

Reference Range

<= 4.0 ng/mL

Clinical Significance

Elevated serum PSA concentrations are found in men with prostate cancer, benign prostatic hypertrophy (BHP) or inflammatory conditions of other adjacent genitourinary tissues, but not in apparently healthy men or in men with cancers other than prostate cancer. When employed for the management of prostate cancer patients, serial measurement of PSA is useful in detecting residual tumor and recurrent cancer after radical prostatectomy. PSA has been demonstrated to be an accurate marker for monitoring advancing clinical stage in untreated patients and for monitoring response to therapy by radical prostatectomy, radiation therapy and anti-androgen therapy.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.