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Dilantin
MessageTest performed at York Hospital Laboratory.
Test Code
PHYT
Alias/See Also
Phenytoin
CPT Codes
80185
Preferred Specimen
0.2 mL serum collected in a serum separator tube (SST)
Other Acceptable Specimens
0.2 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial
Instructions
Phenytoin specimens should be drawn just before the next dose for trough values. If toxicity is suspected, specimens may be drawn at any time.
Separate serum from the cells within 4 hours of collection.
Separate serum from the cells within 4 hours of collection.
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 12 weeks
Refrigerated: 7 days
Frozen: 12 weeks
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimens
Methodology
Immunoassay
Setup Schedule
Daily
Report Available
Next Day
Reference Range
10.0-20.0 mg/L Detection Limit: 3.0 mg/L Critical Values >30.0 mg/L
Clinical Significance
Phenytoin is a widely prescribed anticonvulsant drug used in the treatment of generalized and partial seizures. Phenytoin measurments are used to monitor patient compliance and therapy and to diagnose potential overdose.
