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NT-proBNP2 (N-terminal pro b-type natriuretic peptide 2)
MessageTest performed at York Hospital Laboratory.
Test Code
NBNP2
Alias/See Also
BNP
CPT Codes
83880
Preferred Specimen
0.3 mL serum collected in a serum separator tube (SST)
Other Acceptable Specimens
0.3 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial 0.3 mL plasma collected in a lithium heparin (green-top) gel separator tube
Instructions
Separate serum or plasma from the cells within 4 hours of collection.
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 3 days
Refrigerated: 3 days
Frozen: 12 months
Refrigerated: 3 days
Frozen: 12 months
Methodology
Chemiluminescence
Setup Schedule
Daily
Report Available
Next Day
Available STAT 1/2 Hour
Available STAT 1/2 Hour
Reference Range
>125 - High
Gray Zone: Result Indeterminate Consider Other causes of NT-proBNP elevation.
Age Group: 22 - <50 NT-proBNP 2 Result >=300 - <450
Age Group: 50 - >75 NT-proBNP 2 Result >=300 - <900
Age Group: >=75 NT-proBNP 2 Result >=300 - <1800
Positive:
Age Group: 22 - <50 NT-proBNP2 Result: >=450
Age Group 50 - <75 NT-proBNP2 Result: >=900
Age Group >=75 NT-proBNP2 Result: >=1800
Negative:
Age Group: ALL NT-proBNP2 Result: <300
Gray Zone: Result Indeterminate Consider Other causes of NT-proBNP elevation.
Age Group: 22 - <50 NT-proBNP 2 Result >=300 - <450
Age Group: 50 - >75 NT-proBNP 2 Result >=300 - <900
Age Group: >=75 NT-proBNP 2 Result >=300 - <1800
Positive:
Age Group: 22 - <50 NT-proBNP2 Result: >=450
Age Group 50 - <75 NT-proBNP2 Result: >=900
Age Group >=75 NT-proBNP2 Result: >=1800
Negative:
Age Group: ALL NT-proBNP2 Result: <300
Clinical Significance
The concentration of NT-proBNP indicates the prognosis for left ventricular dysfunction. It is also useful in assigning symptoms to cardiac or non-cardiac causes. Changes in NT-proBNP concentration can be used to evaluate the success of treatment in patients with left ventricular dysfunction.
