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LDH, Total
MessageTest performed at York Hospital Laboratory.
Test Code
LDH
Alias/See Also
Lactate Dehydrogenase, LD
CPT Codes
83615
Preferred Specimen
0.2 mL serum collected in serum separator tube (SST)
Other Acceptable Specimens
0.2 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial 0.2 mL plasma collected in a lithium heparin (green-top) gel separator
Instructions
Do not refrigerate the sample.
Remove the serum or plasma from the cellular material within 1 hours of collection.
Remove the serum or plasma from the cellular material within 1 hours of collection.
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 2 days Refrigerated: Not recommeded Frozen: Not recommended
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimens
Refrigerated specimens
Refrigerated specimens
Methodology
Spectrophotometry
Setup Schedule
Daily
Report Available
Next Day
Reference Range
313-618 U/L
Clinical Significance
Causes of high LDH include neoplastic states, hypoxic cardiorespiratory diseases, myocardial infarctions, hemolytic anemias, megaloblastic anemias, hepatic cirrhosis, renal infarction, trauma, muscle damage, muscular dystrophy, shock, and hypotension. In myocardial infarction cases, LDH begins to rise within about 12 hours after infarction and usually returns to normal after 2-5 days.
