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Digoxin
MessageTest performed at York Hospital Laboratory.
For STAT testing, please notify the lab prior to collecting the specimen.
For STAT testing, please notify the lab prior to collecting the specimen.
Test Code
DIG
Alias/See Also
Dgxn
CPT Codes
80162
Preferred Specimen
0.2 mL serum collected in a serum separator tube (SST)
Other Acceptable Specimens
0.2 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial
Instructions
Digoxin specimens should be drawn at least 6-8 hours after the last dose.
If toxicity is suspected, specimens may be drawn at any time.
If toxicity is suspected, specimens may be drawn at any time.
Transport Temperature
Refrigerated
Specimen Stability
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 4 months
Refrigerated: 7 days
Frozen: 4 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimen
Plasma specimens
Plasma specimens
Methodology
Spectrophotometry
Setup Schedule
Daily
Report Available
Next Day
Available STAT 2 Hours
Available STAT 2 Hours
Reference Range
0.8-2.0 ng/mL
Detection Limit: 0.4 ng/mL
Critical Values
>3.0 ng/mL
Detection Limit: 0.4 ng/mL
Critical Values
>3.0 ng/mL
Clinical Significance
Digoxin is a widely prescribed cardiac glycoside indicated in the treatment of congestive heart failure and supraventricular arrhythmias. Digoxin measurements are used to monitor patient compliance and therapy, and to diagnose potential overdose.
