CK-MB

Message

Test performed at Quest Diagnostics Marlborough
Order Code is QSENT
Quest Marlborough Form Required

Test Code

CKMB

CPT Codes
82553

Includes

CK
CK-MB
Relative Index

Preferred Specimen

0.3 mL serum collected in a serum separator tube (SST)

Other Acceptable Specimens

0.3 mL plasma collected in a lithium heparin (green-top) tube
0.3 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 3 hours
Refrigerated: 5 days
Frozen: 4 weeks

Methodology
Chemiluminescence

Setup Schedule

Daily

Report Available

Next Day

Reference Range

	CK-MB (U/L)
Male	< 4.21
Female	< 2.95

Reference range reflects the 97.5th percentile of a reference control group of normal individuals.

Clinical Significance

The low concentration of CK-MB in normal serum and non-cardiac tissues is the basis of its widely accepted use as a diagnostic indicator of myocardial injury. Damage to the myocardium results in a transient release of CK-MB into the circulation. This increase in CK-MB reaches a peak in 12-24 hours, then returns to normal within 48-72 hours. This characteristic temporal pattern is diagnostic for AMI. Approximately 98% of patients with AMI exhibit elevated serum CK-MB while only 3% of non-AMI patients exhibit abnormal CK-MB.

Performing Laboratory
Quest Diagnostics - Marlborough

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.