Vitamin B12 Reflex

Message

Test performed at York Hospital Laboratory.

Test Code

B12R

CPT Codes
82607

Includes

If B12 is 200-300 pg/ml, a methylmalonic acid, order code METHML will be performed at an additional charge.

Preferred Specimen

2.3 mL serum collected in a serum separator tube (SST)

Minimum Volume

0.8 mL

Other Acceptable Specimens

2.3 mL serum collected in a no additive (red-top) tube, transferred to a plastic screw-cap vial

Instructions

Centrifuge the specimen as soon as possible (within one hour after collection).

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 4 hours
Refrigerated: 7 days
Frozen: 4 weeks

Methodology
Chemiluminescence

Setup Schedule

Daily

Report Available

Next Day

Reference Range

239-931 pg/mL

Clinical Significance

Measurement of vitamin B12 is intended to identify and monitor vitamin B12 deficiency. This can arise from the following: (1) defect in the secretion of Intrinsic Factor, resulting in inadequate absorption from food (pernicious anemia); (2) gastrectomy and malabsorption due to surgical resection; and (3) a variety of bacterial or inflammatory diseases affecting the small intestine.

Additional Information
Reflex Test: Methylmalonic Acid

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.