Celiac Disease Diagnostic Panel

Test Code
QCELD


Quest Code
15681


CPT Codes
82784, 86364 (x2), 86258 (x2)

Includes
Tissue Transglutaminase (tTG) Antibodies (IgG, IgA)
Gliadin (Deamidated) Antibody (IgG, IgA)
IgA (Immunoglobulin A)


Preferred Specimen
3 mL serum


Minimum Volume
1.5 mL


Transport Container
Transport tube


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic


Methodology
See individual tests

Reference Range
Tissue Transglutaminase Antibody, IgG
<15.0 U/mLAntibody not detected
≥15.0 U/mLAntibody detected
Tissue Transglutaminase Antibody, IgA
<15.0 U/mLAntibody not detected
≥15.0 U/mLAntibody detected

Gliadin (Deamidated) Antibody (IgG)
<15.0 U/mLAntibody not detected
≥15.0 U/mLAntibody detected
Gliadin (Deamidated) Antibody (IgA)
<15.0 U/mLAntibody not detected
≥15.0 U/mLAntibody detected

IgA (Immunoglobulin A)
Cord BloodNot Established
≤3 months5-40 mg/dL
4-6 months7-47 mg/dL
7-11 months12-53 mg/dL
1 year20-73 mg/dL
2 years20-99 mg/dL
3-5 years22-140 mg/dL
6-8 years31-180 mg/dL
9-11 years33-200 mg/dL
12-16 years36-220 mg/dL
17-60 years47-310 mg/dL
≥61 years70-320 mg/dL


Clinical Significance
Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.


Performing Laboratory
Quest Diagnostics LLC
200 Forest Street, 3rd Floor, Suite B
Marlborough, MA 01752-3023




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.