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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Saccharomyces cerevisiae Antibodies (ASCA) (IgG, IgA)
Test CodeSACCQ
Quest Code
17609
CPT Codes
86671 (x2)
Preferred Specimen
2 mL serum collected in SST
Minimum Volume
0.6 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 21 days
Refrigerated: 21 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia
Methodology
Immunoassay (IA)
Reference Range
Saccharomyces cerevisiae Ab (ASCA) (IgG)
Saccharomyces cerevisiae Ab (ASCA) (IgA)
| ≤20.0 U | Negative |
| 20.1-29.9 U | Equivocal |
| ≥30.0 U | Positive |
Saccharomyces cerevisiae Ab (ASCA) (IgA)
| ≤20.0 U | Negative |
| 20.1-24.9 U | Equivocal |
| ≥25.0 U | Positive |
Clinical Significance
Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.
Performing Laboratory
| Quest Diagnostics Nichols Institute-Chantilly VA |
| 14225 Newbrook Drive |
| Chantilly, VA 20151-2228 |
