Acetylcholinesterase [4929X]

Test Code
4929X

Includes
This test is automatically performed on all Alpha-Fetoprotein amniotic fluids when the MoM is greater than 1.99.

Preferred Specimen
1.5 mL amniotic fluid collected in a sterile transport tube

Minimum Volume
0.5 mL

Instructions
Indicate gestational age, collection date, clinical indications and the AFP and MoM results, if available, on the test request form.

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 14 days
Rrefrigerated: 4 months
Frozen: 3 years

Methodology
Gel Electrophoresis

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon, Wed, Fri; Report available: 3-6 days

Limitations
Substantial hemorrhage into amniotic fluid may cause AChE and AFP to increase.

Reference Range
Negative

Clinical Significance
Acetylcholinesterase is useful to confirm fetal open neural tube defects and open ventral abdominal wall defects. Hemoglobin F, amniotic fluid is typically ordered simultaneously to exclude the possibility of fetal blood contamination.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Hwy
San Juan Capistrano, CA 92675-2042



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.