Alpha-2-Macroglobulin [228X]

Test Code
228X

Preferred Specimen
1 mL Serum

Minimum Volume
0.5 mL

Other Acceptable Specimens

Serum separator tube



Instructions
Avoid hemolysis. Overnight fasting is preferred. Collect 1 mL serum from a red-top tube (no additive) (preferred). Place serum in a sterile, plastic screw-capped vial. Serum separator tubes are acceptable. Ship refrigerated (cold packs).

Transport Container
Red-top tube (no gel)

Transport Temperature
Refrigerated

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 3 months



Methodology
Fixed Rate Time Nephelometry

Reference Range
106-279 mg/dL

Clinical Significance
Alpha-2- Macroglobulin is produced in the liver.
Increased concentrations are associated with patients
with some chronic liver diseases, nephrotic syndrome, and
diabetes. Decreased concentrations are associated with
patients with pancreatitis, rheumatoid arthritis, and
multiple myeloma.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.