IgA

Test Code

539

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly lipemic

Methodology
Immunoturbidimetric

Setup Schedule

Set up: Mon-Fri; Report available: 1-5 days

Limitations

IgA-deficient individuals may have circulating IgA antibodies that can mediate fatal anaphylactoid reactions if IgA is infused or transfused. The absence IgA antibodies does not necessarily indicate the patient may not suffer anaphalaxis because pre-existing antibodies to other serum proteins may exist and cause anaphalaxis.

Reference Range

Cord Blood	Not Established
≤3 months	5-40 mg/dL
4-6 months	7-47 mg/dL
7-11 months	12-53 mg/dL
1 year	20-73 mg/dL
2 years	20-99 mg/dL
3-5 years	22-140 mg/dL
6-8 years	31-180 mg/dL
9-11 years	33-200 mg/dL
12-16 years	36-220 mg/dL
17-60 years	47-310 mg/dL
≥61 years	70-320 mg/dL

Clinical Significance

Increased IgA is associated with monoclonal IgA myeloma, respiratory and gastrointestinal infections, and malabsorption; decreased IgA is found in selective IgA deficiency and in ataxia telangiectasia.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.