Bile Acids, Fractionated and Total [4668X]

Test Code
116992


Includes
Cholic Acid
Deoxycholic Acid
Chenodeoxycholic Acid
Total Bile Acids


Preferred Specimen
1 mL serum


Patient Preparation
Overnight fasting is preferred

Minimum Volume
0.2 mL


Instructions
Collect blood in a red-top (no gel), or SST tube. After clot formation centrifuge sample and pour off serum into transport tube. Store sample refrigerated or frozen.


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 30 days


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Sun-Fri; Report available: 4-6 days


Reference Range
Cholic Acid≤1.8 umol/L
Deoxycholic Acid≤2.4 umol/L
Chenodeoxycholic Acid≤3.1 umol/L
Total Bile Acids≤6.8 umol/L


Clinical Significance
Bile acids are formed in the liver, from cholesterol, stored and concentrated in the gallbladder, and excreted into the intestines in response to food. Elevated concentrations often suggest impaired hepatic clearance due to liver disease. Patients with intestinal malabsorption and metabolic disorders such as Gilbert's disease do not exhibit elevated bile acids concentrations.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.