Aldosterone, 24-Hour Urine [19552X]

Test Code

Preferred Specimen
5 mL of a 24-hour urine with 10 grams of Boric Acid, submitted in a 24-hour container

Minimum Volume
0.8 mL

Other Acceptable Specimens
24-hour urine collected in 10 grams Boric acid, or random urine collected in a sterile, preservative-free, leak-proof container

Collect urine with 10 grams of Boric Acid to maintain pH below 7.5.

Record 24-hour urine volume on test request form and urine vial. Refrigerate during and after collection.
Sample without preservative is acceptable if kept refrigerated during collection. It is acceptable to add preservative after collection if urine was refrigerated during collection.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 28 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Urine collected with HCl

Extraction • Liquid Chromatography/Tandem Mass Spectrometry • Hydrolysis

Setup Schedule
Set up: Sun, Tues nights; Report available: 4-10 days

Reference Range

Aldosterone, 24-Hour Urine
Random sodium diet


 Age mcg/24 hours 
 2-7 years: 5.7 or less 
8-11 years:  10.2 or less 
12-16 years:  15.6 or less 
 Adults: 2.3-21.0 
 Post Florinef™ or IV saline supression  
 5 mcg/24 hours or less  
 Creatinine, 24 Hour Urine  
 Age  g/24 hours
3-8 years:  0.11-0.68 
 9-12 years: 0.17-1.41 
 13-17 years: 0.29-1.87 
 Adults:  0.63-2.50
 **Reference ranges do not apply to
random urine samples

Clinical Significance
Aldosterone is a hormone produced by the adrenal glands. Patients with primary hyperaldosteronism exhibit hypokalemia, hypertension, and low direct renin concentrations.

Performing Laboratory
Quest Diagnostics Nichols Institute San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.