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Muscle Biopsy for Special Studies
Message
Request test on manual Surgical Pathology Request form (not ordered in computer)
Test Code
Surgical Tissue Muscle Biopsy for Special Studies
Preferred Specimen
Two (acceptable) - three (preferred) cylindrical in shape (2cm X 0.5mm) biopsies with the majority of the fibers running lengthwise. Submit tissue with known muscle disease that shows clinical signs of involvement but that has not reached "end-stage" atrophy. Avoid muscle needed for EMG studies because the latter may cause local reactive inflammation difficult to distinguish from focas of polymyositis. Typically, the triceps, biceps or vastus lateralis is chosen. Ideally the muscle should not be allowed to contract. Pin or clamp muscle to tongue compressor to prevent contraction.
Minimum Volume
Two 2cm X 0.5 mm cylindrical segments, three preferred
Instructions
This test is accepted 8am - 3:30pm Monday thru Friday, excluding holidays and must be scheduled 24 hours in advance with the Pathology department. Submit specimen on saline moistened gauze in a sterile container along with a completed manual "Pathology Specimen Diagnosis Request" form. Provide all essential information including pertinent clinical history. Transport the specimen to the laboratory immediately upon collection.
Transport Container
Sterile container.
Transport Temperature
Keep specimen cool with ice packs, but not frozen
Report Available
Sent to a reference lab. Results may take 48 hours - two weeks
